Mohammed Kudus scored twice and Lucas Paqueta provided all three assists at the London Stadium as West Ham put last week’s 5-0 drubbing by Fulham behind them.
The Ghana forward netted midway through the first period following a swift counter-attack, finishing powerfully after he was found by the impressive Paqueta.
West Ham doubled their advantage in the 32nd minute, when Paqueta and Kudus again combined to deadly effect and top-scorer Jarrod Bowen hit the post with goalkeeper Dan Bentley a bystander.
Wolves thought they had pulled a goal back just before the hour mark but Pablo Sarabia’s tap-in was ruled out for a marginal offside.
West Ham put the result beyond doubt when Bowen finished unerringly after receiving the ball from Paqueta.
On Saturday, Manchester City let slip a 2-0 lead to draw 2-2 with Roy Hodgson’s Crystal Palace, before jetting off to Saudi Arabia to play in the Club World Cup.
It means Liverpool can go six points clear of the defending champions if they beat struggling United at Anfield in the late afternoon kick-off.
Erik ten Hag’s men who last season suffered a 7-0 drubbing at Anfield, have lost 12 of their 24 games in all competitions this season.
With the exception of last season’s 2-1 win at Old Trafford, United’s recent record against Liverpool is dire — they have lost four of the past five meetings, conceding 21 goals in the process.
United captain Bruno Fernandes is suspended while out-of-form Marcus Rashford was once again left on the bench.
Saturday’s Premier League action was overshadowed by a shocking incident at Bournemouth, where Luton captain Tom Lockyer suffered a cardiac arrest, forcing the game to be abandoned.
Luton confirmed Lockyer was responsive before being taken to hospital and was in a “stable” condition. In an update on Sunday the club said he was undergoing tests and scans.
